San Francisco 49ers coach Jim Harbaugh will drive the pace car at Sunday's Indianapolis 500.

Could your birth control be killing you?  Several women claim it almost did.

An FBI agent was involved in a deadly shooting overnight that could have ties to the Boston Marathon bombings, WPTV.com reported.

Anthony Weiner's run for a renaissance is officially on.

The popular lyric, "Ain't no mountain high enough to keep me from you," certainly rings true for this newly engaged couple, after Mel Reyes proposed to Jordie …

Two city officials and three others have been indicted in connection with a federal probe into a bribery scheme involving a program to rebuild the city's most …

For homeowners at the Cedar Cove Condominiums there is something not right about the "Michigan lefts" at 96th Street and Allisonville Road.

Consumers are often not getting what they are paying for, eating more fat than labels indicate.

For 16 seasons, "Dancing with the Stars" has shimmied its way into the hearts (and TV sets) of viewers all around the country.

The Oklahoma elementary school where several children died did not have so-called "safe rooms."

A small southern Indiana town knows what the slow and painful recovery from a tornado is like -- Henryville, Ind., is still rebuilding over a year later.

Hoosiers might be looking at good news at the gas pump this summer. 

Neighbors are pushing for the city to pull the liquor permit for a pancake house where police busted an underage party earlier this year.

Authorities say two children killed in a fire east of Indianapolis Monday suffered "very bad" burns and smoke inhalation.

Oklahoma City Thunder star Kevin Durant is pledging $1 million for tornado relief through his family foundation.

The National Weather Service confirms two EF-0 tornados touched down in Hendricks and Putnam counties early Tuesday.

In response to a class-action lawsuit that alleged the Indiana Bureau of Motor Vehicles overcharged as many as 4 million Hoosiers since 2007, the BMV admitted …

Jodi Arias told a jury Tuesday that she can contribute to society if allowed to live, saying she'd like to start literacy, recycling and other programs in …

A look at the devastation left behind by a massive Oklahoma tornado.